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FEATURES

FAMILY

AB hydrolase superfamily

DESCRIPTION

Also known as PPME1_HUMAN, PPME1, PME1. Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. Binds PPP2CA and PPP2CB.

Also known as PPME1_HUMAN, PPME1, PME1. Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion an ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PPME1

Protein phosphatase methylesterase 1

Molecular Synopsis

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