PPME1 (Protein phosphatase methylesterase 1)

FEATURES

FAMILY

DESCRIPTION

Also known as PPME1_HUMAN, PPME1, PME1. Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme. Binds PPP2CA and PPP2CB.

EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

PPME1

Protein phosphatase methylesterase 1

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

Molecular Synopsis

LIGANDABILITY

APPROVED DRUGS

No approved drugs found

INVESTIGATIONAL DRUGS

No investigational drugs found

CHEMICAL PROBES

STRUCTURAL LIGANDABILITY

NETWORK-BASED

CANCER SCORE

OTHER DISEASES SCORE

CHEMISTRY-BASED

CHEMISTRY-BASED SCORE