FEATURES

FAMILY

DESCRIPTION

Also known as BUP1_HUMAN, UPB1, BUP1. Catalyzes a late step in pyrimidine degradation (PubMed:22525402, PubMed:24526388). Converts N-carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide (PubMed:10542323, PubMed:11508704, PubMed:10415095, PubMed:29976570, PubMed:22525402, PubMed:24526388). Likewise, converts N-carbamoyl-beta-aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide (Probable). Homodimer, homotetramer, homooctamer; can also form higher homooligomers.

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EXTERNAL LINKS

UPB1

Beta-ureidopropionase

ligandability Mutations

UPB1

Molecular Synopsis