FEATURES

FAMILY

DESCRIPTION

Also known as BCD1_HUMAN, ZNHIT6, BCD1, C1orf181. Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis. Interacts with FBL, SNU13, NOP58, NUFIP1, RUVBL1, RUVBL2 and TAF9 (PubMed:17636026). Interacts (via HIT-type zinc finger) with the RUVBL1/RUVBL2 complex in the presence of ADP (PubMed:28561026).

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

ZNHIT6

Box C/D snoRNA protein 1

ligandability Mutations

ZNHIT6

Molecular Synopsis