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nr3c2 (Mineralocorticoid receptor)
FEATURES
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FAMILY
DESCRIPTION
Also known as MCR_ONCMY, nr3c2, mlr. Receptor for both mineralocorticoids (MC) such as cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity).
Also known as MCR_ONCMY, nr3c2, mlr. Receptor for both mineralocorticoids (MC) such as cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity).
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nr3c2

Mineralocorticoid receptor

Molecular Synopsis