TRPC7 (Short transient receptor potential channel 7)

FEATURES

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FAMILY

transient receptor (TC 1.A.4) family

DESCRIPTION

Also known as TRPC7_HUMAN, TRPC7, TRP7. Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. Interacts with MX1 and RNF24. Interacts (via ANK-repeat domains) with PRKG1.

Also known as TRPC7_HUMAN, TRPC7, TRP7. Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracel ...

EXTERNAL LINKS

TRPC7

Short transient receptor potential channel 7

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

Molecular Synopsis

LIGANDABILITY

APPROVED DRUGS

No approved drugs found

INVESTIGATIONAL DRUGS

No investigational drugs found

CHEMICAL PROBES

STRUCTURAL LIGANDABILITY

NETWORK-BASED

CANCER SCORE

OTHER DISEASES SCORE

CHEMISTRY-BASED

CHEMISTRY-BASED SCORE