FEATURES

FAMILY

DESCRIPTION

Also known as QTRT2_HUMAN, QTRT2, QTRTD1. Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4, 5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.

... More

EXTERNAL LINKS

QTRT2

Queuine tRNA-ribosyltransferase accessory subunit 2

ligandability Mutations

QTRT2

Molecular Synopsis