CIAO3 (Cytosolic iron-sulfur assembly component 3)

FEATURES

FAMILY

DESCRIPTION

Also known as CIAO3_HUMAN, CIAO3, NARFL, PRN. Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect. External component of the CIA complex (PubMed:22678361, PubMed:22678362, PubMed:23585563). In the CIA complex, interacts directly with CIAO1 and MMS19 (PubMed:23585563).

... More

EXTERNAL LINKS

CIAO3

Cytosolic iron-sulfur assembly component 3

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

CIAO3

Molecular Synopsis