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GNL1 (ARF guanine-nucleotide exchange factor GNL1)
FEATURES
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DESCRIPTION
Also known as GNL1_ARATH, GNL1, ERMO1, GBF1. Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of retrograde Golgi to endoplasmic reticulum trafficking but is also involved in the endocytosis process. Could function redundantly with GNOM. Regulates vesicle trafficking required for the coordinated polar localization of auxin efflux carriers which in turn determines the direction of auxin flow. Mediates the endocytosis of PIN2 from plasma membrane to endosomal compartments. Required for maintenance of endoplasmic reticulum morphology. Homodimer.
Also known as GNL1_ARATH, GNL1, ERMO1, GBF1. Activates the ARF proteins by exchanging bound GDP for free GTP. Plays a role in vesicular protein sorting. Acts as the major regulator of retrograde Golgi to endoplasmic reticulum trafficking but is also involved in the endocytosis process. Could function redundantly with GNOM. Regulates vesicle traffic ... More
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GNL1

ARF guanine-nucleotide exchange factor GNL1

Molecular Synopsis