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SWC6 (SWR1 complex subunit 6)
FEATURES
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FAMILY
DESCRIPTION
Also known as SWC6_ARATH, SWC6, SEF. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Coodinates SWR1-C, FRI-C (FLC transcription activator complex), histone methyltransferase and general transcription factors. Represses flowering by positively regulating FLC and MAF4. Binds to the promoter region of FLC chromatin. Homodimer. Component of the SWR1 chromatin-remodeling complex composed of at least ARP6/ESD1/SUF3, PIE1, SWC6, SWC2 and H2AZs (HTA8, HTA9, HTA11). Interacts directly with ARP6, PIE1 and SWC2. Interacts with FLX and SUF4, two component of the transcription activator complex FRI-C, and with ASHH2 and TAF14.
Also known as SWC6_ARATH, SWC6, SEF. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Coodinates SWR1-C, FRI-C (FLC transcription activator complex), histone methyltransferase and general tran ... More
SWC6 logo

SWC6

SWR1 complex subunit 6

Molecular Synopsis