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Pdcl (Phosducin-like protein)
FEATURES
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FAMILY
DESCRIPTION
Also known as PHLP_MOUSE, Pdcl, PhLP1. Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers (PubMed:23637185). Acts also as a positive regulator of hedgehog signaling and regulates ciliary function (PubMed:29290584). Forms a complex with the beta and gamma subunits of the GTP-binding protein, transducin. Interacts with the CCT chaperonin complex (By similarity).
Also known as PHLP_MOUSE, Pdcl, PhLP1. Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers (PubMed:23637185). Acts also as a positive regulator of hedgehog signaling and regulates ciliary function (PubMed:29290584). Forms a complex with ... More
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Pdcl

Phosducin-like protein

Molecular Synopsis