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Fam83d (Protein FAM83D)
FEATURES
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FAMILY
DESCRIPTION
Also known as FA83D_MOUSE, Fam83d. Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade. May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22. Interacts with FBXW7; promotes FBXW7 degradation. May interact with RAF1. Interacts with KIF22; recruits KIF22 to mitotic spindle microtubules.
Also known as FA83D_MOUSE, Fam83d. Probable proto-oncogene that regulates cell proliferation, growth, migration and epithelial to mesenchymal transition. Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC. May play also a role in cell proliferation through activation of the ERK1/ERK2 ... More
Fam83d logo

Fam83d

Protein FAM83D

Molecular Synopsis