Gpihbp1 logo
Gpihbp1 (Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1)
FEATURES
Loading...
Loading...
DESCRIPTION
Also known as HDBP1_MOUSE, Gpihbp1, Hbp1. Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (PubMed:20620994). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (PubMed:20620994, PubMed:24726386, PubMed:27811232). Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis (PubMed:17403372). Binds chylomicrons and phospholipid particles that contain APOA5 (PubMed:18340083). Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL (PubMed:12496272). Mostly monomer, but also homodimer and homooligomer (PubMed:25387803). Interacts with lipoprotein lipase (LPL) (PubMed:17403372, PubMed:18340083, PubMed:19304573, PubMed:20620994, PubMed:25387803, PubMed:24726386, PubMed:27811232). Interacts with high affinity with high-density lipoprotein (HDL) (PubMed:12496272). Interacts with chylomicrons (PubMed:17403372). Interacts with APOA5 (PubMed:18340083).
Also known as HDBP1_MOUSE, Gpihbp1, Hbp1. Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries (PubMed:20620994). Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries (PubMed:20620994, PubMed:24726386, PubMed:27811232). Thereby, plays an importan ... More
Gpihbp1 logo

Gpihbp1

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

Molecular Synopsis