FEATURES

FAMILY

DESCRIPTION

Also known as KRA45_HUMAN, KRTAP4-5, KAP4.5, KRTAP4.5. In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. Interacts with hair keratins.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

KRTAP4-5

Keratin-associated protein 4-5

ligandability Mutations

KRTAP4-5

Molecular Synopsis