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NSUN5 (Probable 28S rRNA (cytosine-C(5))-methyltransferase)
FEATURES
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FAMILY
DESCRIPTION
Also known as NSUN5_HUMAN, NSUN5, NSUN5A, WBSCR20, WBSCR20A. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 in 28S rRNA.
Also known as NSUN5_HUMAN, NSUN5, NSUN5A, WBSCR20, WBSCR20A. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 3782 in 28S rRNA.
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NSUN5

Probable 28S rRNA (cytosine-C(5))-methyltransferase

Copy number variation

DiseaseSignal Cell linesGain Cell linesAvg. ampLoss Cell linesAvg. lossNo-signal Cell linesAvg. change
cancer 1 0 1 0.47 146 1.10
NS 1 0 1 0.47 152 1.13
carcinoma 5 2 2.06 3 0.37 547 1.10
haematopoietic_neoplasm 0 0 0 63 1.07
leukaemia 0 0 0 84 1.07
lymphoid_neoplasm 0 0 0 135 1.12
glioma 0 0 0 52 1.26
malignant_melanoma 0 0 0 56 1.27
melanoma 0 0 0 43 1.28
glioblastoma 0 0 0 2 1.26

Cell lines

Cell lineSignalCopy numberAvg. genome ploidyAmplificationDiseaseTissue
22Rv-1 No signal 2 2.04 0.98 cancer, NS, carcinoma prostate
5637 No signal 4 2.99 1.34 cancer, carcinoma bladder, urinary_tract
639-V No signal 1 2.41 0.42 cancer, carcinoma bladder, ureter, urinary_tract
647-V No signal 2 2.50 0.80 cancer, carcinoma bladder, urinary_tract
697 No signal 2 1.98 1.01 haematopoietic_neoplasm, leukaemia, lymphoid_neoplasm blood_bone_marrow, haematopoietic_and_lymphoid_tissue
769-P No signal 2 1.97 1.02 carcinoma kidney
786-0 No signal 5 3.82 1.31 cancer, carcinoma kidney
8-MG-BA No signal 2 2.20 0.91 glioma brain, central_nervous_system
8305C Loss 1 3.09 0.32 carcinoma thyroid
8505C No signal 3 3.00 1.00 carcinoma thyroid