FEATURES

FAMILY

DESCRIPTION

Also known as NUOC_RALSO, nuoC. NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.

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EXTERNAL LINKS

nuoC

NADH-quinone oxidoreductase subunit C

ligandability Mutations

nuoC

Molecular Synopsis