FEATURES

FAMILY

DESCRIPTION

Also known as ZC3HF_HUMAN, ZC3H15, DFRP1, LEREPO4. Protects DRG1 from proteolytic degradation (PubMed:19819225). Stimulates DRG1 GTPase activity likely by increasing the affinity for the potassium ions (PubMed:23711155). Interacts with DRG1; this interaction prevents DRG1 poly-ubiquitination and degradation by proteasome. DRG1-ZC3H15/DFRP1 complex co-sediments with polysomes. Associates with microtubules.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

ZC3H15

Zinc finger CCCH domain-containing protein 15

ligandability Mutations

ZC3H15

Molecular Synopsis