rnp2 (Ribonuclease P protein component 2)

FEATURES

FAMILY

eukaryotic/archaeal RNase P protein component 2 family

DESCRIPTION

Also known as RNP2_PYRFU, rnp2. Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. The RNA is catalytic, but its KM for pre-tRNA is 170-fold decreased in the presence of the 4 known protein subunits (Rnp1-4). The protein subunits also decrease the amount of Mg(2+) needed for activity. Consists of a catalytic RNA component and at least 4-5 protein subunits. Forms a subcomplex with Rnp3 which stimulates the catalytic RNA.

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EXTERNAL LINKS

rnp2

Ribonuclease P protein component 2

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

rnp2

Molecular Synopsis