DOT1L logo
DOT1L (Histone-lysine N-methyltransferase, H3 lysine-79 specific)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as DOT1L_HUMAN, DOT1L, KIAA1814, KMT4. Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones (PubMed:12123582). Binds to DNA (PubMed:12628190). Interacts with MLLT10.
Also known as DOT1L_HUMAN, DOT1L, KIAA1814, KMT4. Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones (PubMed:12123582). Binds to DNA (PubMed:12628190). Interacts with MLLT10.
DOT1L logo

DOT1L

Histone-lysine N-methyltransferase, H3 lysine-79 specific

Molecular Synopsis

LIGANDABILITY
APPROVED DRUGS
No approved drugs found
INVESTIGATIONAL DRUGS
No investigational drugs found
CHEMICAL PROBES
Probe Miner logo
Chemical Probes logo
NETWORK-BASED
CANCER SCORE
OTHER DISEASES SCORE
CHEMISTRY-BASED
CHEMISTRY-BASED SCORE