AGR3 logo
AGR3 (Anterior gradient protein 3)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as AGR3_HUMAN, AGR3, BCMP11, PDIA18. Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells. Interacts with LYPD3 and DAG1 (alphaDAG1).
Also known as AGR3_HUMAN, AGR3, BCMP11, PDIA18. Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells. Interacts with LYPD3 and DAG1 (alphaDAG1).
AGR3 logo

AGR3

Anterior gradient protein 3

Copy number variation

DiseaseSignal Cell linesGain Cell linesAvg. ampLoss Cell linesAvg. lossNo-signal Cell linesAvg. change
cancer 2 2 2.03 0 145 1.19
NS 1 1 2.25 0 152 1.21
carcinoma 11 10 2.07 1 0.32 541 1.21
haematopoietic_neoplasm 1 0 1 0.49 62 1.01
leukaemia 1 0 1 0.49 83 1.01
lymphoid_neoplasm 1 0 1 0.49 134 1.08
glioma 0 0 0 52 1.48
malignant_melanoma 1 1 2.33 0 55 1.32
melanoma 1 1 2.33 0 42 1.35
glioblastoma 0 0 0 2 1.26

Cell lines

Cell lineSignalCopy numberAvg. genome ploidyAmplificationDiseaseTissue
22Rv-1 No signal 3 2.04 1.47 cancer, NS, carcinoma prostate
5637 No signal 4 2.99 1.34 cancer, carcinoma bladder, urinary_tract
639-V No signal 4 2.41 1.66 cancer, carcinoma bladder, ureter, urinary_tract
647-V No signal 4 2.50 1.60 cancer, carcinoma bladder, urinary_tract
697 No signal 2 1.98 1.01 haematopoietic_neoplasm, leukaemia, lymphoid_neoplasm blood_bone_marrow, haematopoietic_and_lymphoid_tissue
769-P No signal 2 1.97 1.02 carcinoma kidney
786-0 No signal 5 3.82 1.31 cancer, carcinoma kidney
8-MG-BA No signal 3 2.20 1.37 glioma brain, central_nervous_system
8305C Loss 1 3.09 0.32 carcinoma thyroid
8505C No signal 4 3.00 1.33 carcinoma thyroid