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MRAP (Melanocortin-2 receptor accessory protein)
FEATURES
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FAMILY
DESCRIPTION
Also known as MRAP_HUMAN, MRAP, C21orf61, FALP. Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells. Homodimer and heterodimer. Forms antiparallel homodimers and heterodimers with MRAP2. Interacts with MC1R, MC2R, MC3R, MC4R and MC5R.
Also known as MRAP_HUMAN, MRAP, C21orf61, FALP. Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotrop ...
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MRAP

Melanocortin-2 receptor accessory protein

Evidence from Cancer Cell Lines