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NT5C (5'(3')-deoxyribonucleotidase, cytosolic type)
FEATURES
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FAMILY
DESCRIPTION
Also known as NT5C_HUMAN, NT5C, DNT1, UMPH2. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. Homodimer.
Also known as NT5C_HUMAN, NT5C, DNT1, UMPH2. Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP. Homodimer.
NT5C logo

NT5C

5'(3')-deoxyribonucleotidase, cytosolic type

Expression

StudyTumor samplesMaxQ3Q2Q1MinNormal samplesMaxQ3Q2Q1MinLog2 (T vs N)
Adrenocortical (ACC) 77 2.04 1.70 1.56 1.44 1.07 126 11.49 1.70 1.65 1.60 1.46 -0.09
Bladder (BLCA) 406 2.55 1.91 1.78 1.66 0.61 9 1.79 1.77 1.71 1.68 1.64 0.07
Breast (BRCA) 1067 2.43 1.60 1.46 1.36 0.36 178 2.08 1.70 1.65 1.60 1.45 -0.19
Cervical (CESC) 297 2.73 1.82 1.71 1.60 1.28 10 1.89 1.84 1.77 1.69 1.61 -0.06
Cholangiocarcinoma (CHOL) 36 2.26 1.93 1.78 1.64 1.44 0
Colon (COAD) 443 2.34 1.87 1.77 1.67 0.22 166 2.14 1.93 1.82 1.69 1.37 -0.05
B-cell lymphoma (DLBC) 42 2.29 2.14 1.99 1.78 1.49 337 2.38 1.90 1.78 1.68 0.27 0.20
Esophageal (ESCA) 142 2.07 1.59 1.49 1.40 1.10 271 2.11 1.83 1.77 1.70 1.53 -0.28
Glioblastoma (GBM) 160 1.77 1.58 1.50 1.43 1.18 214 11.43 1.73 1.64 1.58 0.43 -0.14
Head and neck (HNSC) 432 2.43 1.82 1.72 1.60 1.01 55 1.84 1.64 1.59 1.53 1.39 0.13