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AEP2 (Neurotoxin BmKAEP2)
FEATURES
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FAMILY
DESCRIPTION
Also known as AEP2_MESMA, AEP2. Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on insects. Has potential anti-epilepsy effect (By similarity).
Also known as AEP2_MESMA, AEP2. Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and r ...
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AEP2

Neurotoxin BmKAEP2

Molecular Synopsis