fliT (Flagellar protein FliT)

FEATURES

FAMILY

DESCRIPTION

Also known as FLIT_SHIFL, fliT. Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. Homodimer. Interacts with FliD and FlhC.

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EXTERNAL LINKS

fliT

Flagellar protein FliT

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

fliT

Molecular Synopsis