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siah1 (E3 ubiquitin-protein ligase Siah1)
FEATURES
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FAMILY
DESCRIPTION
Also known as SIAH1_DANRE, siah1. E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates. Homodimer.
Also known as SIAH1_DANRE, siah1. E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiq ... More
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siah1

E3 ubiquitin-protein ligase Siah1

Molecular Synopsis