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canA (Serine/threonine-protein phosphatase 2B catalytic subunit)
FEATURES
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FAMILY
DESCRIPTION
Also known as PP2BA_DICDI, canA. Catalytic subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Forms a complex composed of a catalytic and calmodulin-dependent subunit, calcineurin A, and a regulatory Ca(2+)-binding subunit, calcineurin B (PubMed:11352578). In response to an increase in Ca(2+) intracellular levels, forms a complex composed of canA/calcineurin A, cnbA/calcineurin B and calA/calmodulin (PubMed:11352578). Interacts (via calcineurin B binding domain) with regulatory subunit cnbA/calcineurin B (PubMed:11352578). Interacts (via calmodulin-binding domain) with calmodulin; the interaction depends on calmodulin binding to Ca(2+) (PubMed:10608845, PubMed:11352578).
Also known as PP2BA_DICDI, canA. Catalytic subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Forms a complex composed of a catalytic and calmodulin-dependent subunit, calcineurin A, and a regulatory Ca(2+)-binding subunit ... More
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canA

Serine/threonine-protein phosphatase 2B catalytic subunit

Molecular Synopsis