glvI (Proton-gated ion channel)

FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as GLIC_GLOVI, glvI. Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change. Homopentamer.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

glvI

Proton-gated ion channel

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

glvI

Molecular Synopsis