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ORF12 (SAR-endolysin)
FEATURES
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FAMILY
DESCRIPTION
Also known as ENLYS_BPT1, ORF12. Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature viral particles. Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm where it breaks down the peptidoglycan layer.
Also known as ENLYS_BPT1, ORF12. Signal-arrest-release (SAR) endolysin with lysozyme activity that degrades host peptidoglycans and participates with the pinholin and spanin proteins in the sequential events which lead to programmed host cell lysis releasing the mature viral particles. Once the pinholin has permeabilized the host cell membrane, the ...
ORF12 logo

ORF12

SAR-endolysin

Molecular Synopsis