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PSRC1 (Proline/serine-rich coiled-coil protein 1)
FEATURES
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FAMILY
DESCRIPTION
Also known as PSRC1_HUMAN, PSRC1, DDA3. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression. Interacts with APC2 (By similarity). Interacts with KIF2A (PubMed:18411309). Interacts with ANKRD53; recruits ANKRD53 to the spindle during mitosis (PubMed:26820536).
Also known as PSRC1_HUMAN, PSRC1, DDA3. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, ...
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PSRC1

Proline/serine-rich coiled-coil protein 1

Molecular Synopsis