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Alkbh2 (DNA oxidative demethylase ALKBH2)
FEATURES
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FAMILY
DESCRIPTION
Also known as ALKB2_MOUSE, Alkbh2, Abh2. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
Also known as ALKB2_MOUSE, Alkbh2, Abh2. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, al ...
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Alkbh2

DNA oxidative demethylase ALKBH2

Molecular Synopsis