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Hecw2 (E3 ubiquitin-protein ligase HECW2)
FEATURES
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DESCRIPTION
Also known as HECW2_MOUSE, Hecw2, Kiaa1301, Nedl2. E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition. Interacts with TP73 (By similarity). Interacts with FZR1 (By similarity).
Also known as HECW2_MOUSE, Hecw2, Kiaa1301, Nedl2. E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Involved in the regulation of mitotic metaphase/anaphase transition. Interacts with TP73 (By similarity). Interacts with FZR1 (By similarity).
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Hecw2

E3 ubiquitin-protein ligase HECW2

Molecular Synopsis