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APOBEC1 (C->U-editing enzyme APOBEC-1)
FEATURES
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FAMILY
DESCRIPTION
Also known as ABEC1_PONPY, APOBEC1. Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. Homodimer. Part of the apolipoprotein B mRNA editing complex with APC. Interacts with HNRPAB and SYNCRIP.
Also known as ABEC1_PONPY, APOBEC1. Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of ge ... More
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APOBEC1

C->U-editing enzyme APOBEC-1

Molecular Synopsis