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leuA (2-isopropylmalate synthase)
FEATURES
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FAMILY
DESCRIPTION
Also known as LEU1_BACLD, leuA. Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Homotetramer.
Also known as LEU1_BACLD, leuA. Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Homotetramer.
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leuA

2-isopropylmalate synthase

Molecular Synopsis