glyA2 logo
glyA2 (Serine hydroxymethyltransferase 2)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as GLYA2_BURPS, glyA2. Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Homodimer.
Also known as GLYA2_BURPS, glyA2. Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independe ... More
glyA2 logo

glyA2

Serine hydroxymethyltransferase 2

Molecular Synopsis