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bopE (Guanine nucleotide exchange factor BopE)
FEATURES
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FAMILY
DESCRIPTION
Also known as BOPE_BURPS, bopE. Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells. Monomer (Probable). Interacts with human CDC42.
Also known as BOPE_BURPS, bopE. Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells. Monomer (Probable). Intera ... More
bopE logo

bopE

Guanine nucleotide exchange factor BopE

Molecular Synopsis