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Cdk16 (Cyclin-dependent kinase 16)
FEATURES
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FAMILY
DESCRIPTION
Also known as CDK16_RAT, Cdk16, Pctaire1, Pctk1. Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Can phosphorylate CCNY at 'Ser-336' (in vitro) Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Regulates GH1 release by brain neurons. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Phosphorylates NSF, and thereby regulates NSF oligomerization. Interacts with BRSK2. Interacts with CCNY; this increases the CDK16 kinase activity (By similarity). Found in a complex containing CABLES1, CDK17 and TDRD7. Interacts with YWHAH, YWHAQ and YWHAZ. Interacts with NSF. Identified in a complex with NSF, syntaxin-1, synaptotagmin, SYN1, SYP and CDK5R1.
Also known as CDK16_RAT, Cdk16, Pctaire1, Pctk1. Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Can phosphorylate CCNY at 'Ser-336' (in vitro) Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Regulates GH1 release by brain neurons. Required for normal sperm ... More
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Cdk16

Cyclin-dependent kinase 16

Molecular Synopsis