secs-1 (O-phosphoseryl-tRNA(Sec) selenium transferase)

FEATURES

FAMILY

DESCRIPTION

Also known as SPCS_CAEBR, secs-1. Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION

secs-1

O-phosphoseryl-tRNA(Sec) selenium transferase

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

secs-1

Molecular Synopsis