LIN9 logo
LIN9 (Protein lin-9 homolog)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as LIN9_HUMAN, LIN9, BARA, TGS. Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL2. Interacts with RB1.
Also known as LIN9_HUMAN, LIN9, BARA, TGS. Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition. Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F ...
LIN9 logo

LIN9

Protein lin-9 homolog

Germline Genetics

No germline genetics data available for LIN9.