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PLA1A (Phospholipase A1 member A)
FEATURES
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FAMILY
DESCRIPTION
Also known as PLA1A_HUMAN, PLA1A, NMD, PSPLA1. Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.
Also known as PLA1A_HUMAN, PLA1A, NMD, PSPLA1. Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidi ...
PLA1A logo

PLA1A

Phospholipase A1 member A

Interactome

PLA1A is reported in 2 pathways.
Provide LogoProviderPathway sizePathway name
5-arachidonylglycerol_biosynthesis logo
PANTHER Pathways 3.4.1 on 04-Jul-2016 (auto-converted to human-only model) 7 5-arachidonylglycerol_biosynthesis
Acyl chain remodelling of PS logo
Reactome v61 (only 'Homo_sapiens.owl') 23-Jun-2017 22 Acyl chain remodelling of PS