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PLA1A (Phospholipase A1 member A)
FEATURES
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FAMILY
DESCRIPTION
Also known as PLA1A_HUMAN, PLA1A, NMD, PSPLA1. Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.
Also known as PLA1A_HUMAN, PLA1A, NMD, PSPLA1. Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidi ...
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PLA1A

Phospholipase A1 member A

Expression

StudyTumor samplesMaxQ3Q2Q1MinNormal samplesMaxQ3Q2Q1MinLog2 (T vs N)
Adrenocortical (ACC) 77 2.15 0.73 0.60 0.27 -0.00 126 0.92 0.47 0.35 0.21 -0.01 0.25
Bladder (BLCA) 406 2.48 1.02 0.70 0.46 -0.01 9 0.74 0.63 0.49 0.33 -0.03 0.21
Breast (BRCA) 1067 2.18 1.06 0.86 0.67 -0.01 178 1.55 1.08 0.85 0.67 0.02 0.01
Cervical (CESC) 297 1.94 1.05 0.78 0.45 -0.02 10 1.57 1.42 0.90 0.77 0.50 -0.13
Cholangiocarcinoma (CHOL) 36 2.37 1.49 1.24 1.17 0.55 0
Colon (COAD) 443 1.81 1.21 0.98 0.74 -0.03 166 1.49 0.86 0.70 0.57 -0.09 0.28
B-cell lymphoma (DLBC) 42 1.95 1.57 1.35 1.10 0.55 337 1.26 0.03 -0.46 -0.23 -0.00 1.80
Esophageal (ESCA) 142 1.87 0.91 0.62 0.30 -0.03 271 1.56 0.69 0.52 0.36 -0.02 0.10
Glioblastoma (GBM) 160 1.15 0.53 0.35 0.15 -0.00 214 1.46 0.82 0.53 0.34 -0.04 -0.18
Head and neck (HNSC) 432 1.58 0.81 0.56 0.31 -0.00 55 1.45 0.72 0.58 0.36 0.17 -0.02