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mtnP (S-methyl-5'-thioadenosine phosphorylase)
FEATURES
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FAMILY
DESCRIPTION
Also known as MTAP_KORVE, mtnP. Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. Homohexamer. Dimer of a homotrimer.
Also known as MTAP_KORVE, mtnP. Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethio ... More
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mtnP

S-methyl-5'-thioadenosine phosphorylase

Molecular Synopsis