FEATURES

FAMILY

DESCRIPTION

Also known as CP2AD_HUMAN, CYP2A13. Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N, N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity.

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EXTERNAL LINKS

UNIPROT
ENZYME CLASSIFICATION
PhosphoSitePlus

CYP2A13

Cytochrome P450 2A13

ligandability Mutations

CYP2A13

Molecular Synopsis