FEATURES

FAMILY

DESCRIPTION

Also known as GRM4_HUMAN, GRM4, GPRC1D, MGLUR4. G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. Interacts with PICK1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GRM4

Metabotropic glutamate receptor 4

GRM4

Molecular Synopsis