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FOLH1 (Glutamate carboxypeptidase 2)
FEATURES
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FAMILY
DESCRIPTION
Also known as FOLH1_HUMAN, FOLH1, FOLH, NAALAD1, PSM, PSMA. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression., Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. Homodimer.
Also known as FOLH1_HUMAN, FOLH1, FOLH, NAALAD1, PSM, PSMA. Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neurop ...
FOLH1 logo

FOLH1

Glutamate carboxypeptidase 2

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3D7D_A
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