MGR3 (Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3)

FEATURES

FAMILY

DESCRIPTION

Also known as MGR3_YEAST, MGR3, FMP24. Component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. Together with MGR1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation. Required for growth of cells lacking the mitochondrial genome. Component of the mitochondrial inner membrane i-AAA protease supercomplex composed of MGR1, MGR3 and YME1. With MGR1, forms a subcomplex that binds to YME1 and to substrates to facilitate proteolysis.

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EXTERNAL LINKS

MGR3

Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3

MOLECULAR SYNOPSIS STRUCTURAL LIGANDABILITY

MGR3

Molecular Synopsis