ROR2 logo
ROR2 (Tyrosine-protein kinase transmembrane receptor ROR2)
FEATURES
Loading...
Loading...
FAMILY
DESCRIPTION
Also known as ROR2_HUMAN, ROR2, NTRKR2. Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443). Homodimer; promotes osteogenesis. Binds YWHAB (PubMed:17717073). Interacts with WTIP (By similarity).
Also known as ROR2_HUMAN, ROR2, NTRKR2. Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been sho ...
ROR2 logo

ROR2

Tyrosine-protein kinase transmembrane receptor ROR2

3D Viewer

4GT4_A
Loading...