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rslA (Anti-sigma-L factor RslA)
FEATURES
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FAMILY
DESCRIPTION
Also known as RSLA_MYCTO, rslA. An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigL. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor (By similarity). Interacts with ECF RNA polymerase sigma factor SigL; this should inhibit the interaction of SigL with the RNA polymerase catalytic core.
Also known as RSLA_MYCTO, rslA. An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigL. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information an ... More
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rslA

Anti-sigma-L factor RslA

Molecular Synopsis