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rsmA (Anti-sigma-M factor RsmA)
FEATURES
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DESCRIPTION
Also known as RSMAF_MYCTO, rsmA. An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigM. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor (By similarity). Interacts with ECF RNA polymerase sigma factor SigM; this should inhibit the interaction of SigM with the RNA polymerase catalytic core.
Also known as RSMAF_MYCTO, rsmA. An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigM. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information a ... More
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rsmA

Anti-sigma-M factor RsmA

Molecular Synopsis