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sigF (RNA polymerase sigma factor SigF)
FEATURES
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FAMILY
DESCRIPTION
Also known as SIGF_MYCTO, sigF. Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Held in an inactive form by a cognate anti-sigma factor RsbW (UsfX) until released. Its regulon, determined following disruption, consists of 38 genes decreased in exponential phase, 187 genes decreased in early S-phase, and 277 genes decreased in late S-phase (PubMed:14977982). Monomer. Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. Interacts (via sigma-70 factor domain 4) with anti-sigma-F factor RsbW (UsfX) (By similarity).
Also known as SIGF_MYCTO, sigF. Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Held in an inactive form by a cognate anti-sigma factor RsbW (UsfX) until released. Its regulon, determined following disruption, consists of 38 genes decreased in exponential phase, ... More
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sigF

RNA polymerase sigma factor SigF

Molecular Synopsis