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14-3-3epsilon (14-3-3 protein epsilon)
FEATURES
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FAMILY
DESCRIPTION
Also known as 1433E_DROME, 14-3-3epsilon, 14-3-3e, SR3-9. Positively regulates Ras-mediated pathways. Acts downstream or parallel to Raf, but upstream of nuclear factors in Ras signaling. Three mutants have been isolated, that suppress the rough eye phenotype caused by mutated Ras1 (sev-Ras1 v12). Inhibits yki activity by restricting its nuclear localization. Homodimer (By similarity). Interacts with phosphorylated yki.
Also known as 1433E_DROME, 14-3-3epsilon, 14-3-3e, SR3-9. Positively regulates Ras-mediated pathways. Acts downstream or parallel to Raf, but upstream of nuclear factors in Ras signaling. Three mutants have been isolated, that suppress the rough eye phenotype caused by mutated Ras1 (sev-Ras1 v12). Inhibits yki activity by restricting its nuclear lo ... More
14-3-3epsilon logo

14-3-3epsilon

14-3-3 protein epsilon

Molecular Synopsis