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(Replication origin-binding protein)
FEATURES
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FAMILY
DESCRIPTION
Also known as OBP_HHV2H. Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins. In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication. Homodimer. Interacts with the major DNA-binding protein ICP8. Interacts with the helicase/primase component UL8 and the polymerase accessory protein UL42 (By similarity).
Also known as OBP_HHV2H. Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins. In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication. Homodimer. Interacts with the major ... More
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Replication origin-binding protein

Molecular Synopsis